A Discovery Platform for Next-Gen Drug Innovations
Shuimu Biosciences (水木未来, also known as Shuimu Future) is a rapidly evolving global cryo-EM (CryoEM / CryoTEM) & AIDD platform dedicated to early drug discovery. Equipped with 8 state-of-the-art 300kV cryo-EM instruments, Shuimu drives innovation in structural biology — from antibody structure determination and GPR75 studies to SPA and cryo-ET tomography (TOMO) — to accelerate the development of groundbreaking drugs.
Partner With UsBetter Accessibility
With eight 300kV TEMs at full load, we are expanding capacity to make cryo-EM more accessible to partners around the world.
Competent Team & Techs
We invest in top cryo-EM experts and innovative technologies to deliver quality projects and better applicability.
One-Stop Capability
Powerful cryo-EM data collection centers and an in-house protein production laboratory for sequence-to-structure solutions.
Shuimu Cryo-EM Platform



COFOUNDERS
Started with a belief in cryo-EM

Hongwei Wang, PhD
Chair of Shuimu Scientific Advisory Board
Dean of Institute of Biomedicine, Tsinghua University. 20+ year experience in cryo-EM methodology and its application in structural biology.

Qiangfeng Zhang, PhD
Director of Shuimu Research Institute
Professor at School of Life Sciences, Tsinghua University. Developer of modelSMART, a deep learning algorithm for atomic structure modeling.

Allen Guo
CEO
Serial entrepreneur, and seasoned investor with over 20 years of experience in the technology industry.
Scientific Advisory Board
On the shoulders of great minds we jump

Yifan Cheng, PhD
Cryo-EM Scientist
Member of AAAS and NAS, Professor at UCSF, Investigator of HHMI, Developed a direct electron detection camera in cryo-EM and significantly improved SPA resolution to 3.4 Å.

Xueming Li, PhD
Expert in Electron Microscope & Data Processing
Professor at School of Life Sciences, Tsinghua University. Expert in electron microscopes and data processing.

Jianlin Lei, PhD
Expert in Cryo-EM Platform
Director of Cryo-EM Platform at Tsinghua University. Developer of AutoEMation, an automated data collection software.

Hai Qi, PhD
Immunologist
Dean of School of Medicine, Tsinghua University. Promoted the renewal and revision of Tfh generation mechanism and development theory.

Guangshuo Ou, PhD
Cell Biologist
Professor at School of Life Sciences, Tsinghua University. Committed to structural biology research based on nematode models.

Li Yu, PhD
Cell Biologist
Professor at School of Life Sciences, Tsinghua University. Discoverer of a new organelle migrating body.
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