Sample quality assessment
Cryo-EM Characterization
Comprehensive sample screening and quality assessment using advanced cryo-EM techniques to ensure optimal conditions for high-resolution structure determination.
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Workflow
Sample Receipt
Initial quality check and documentation
Grid Preparation
Test grid preparation under various conditions
Microscope Screening
Low-magnification screening on 120kV Talos
Report & Recommendations
Detailed assessment report with optimization suggestions
Why Choose Shuimu?
Rapid Turnaround
Quick assessment to guide sample optimization before full data collection
Expert Guidance
PhD scientists provide recommendations for sample improvement
Structures Solved by Shuimu
Explore Other Services
Cryo-EM SPA
Single Particle Analysis (SPA) for high-resolution protein structure determination — antibody structures, GPCRs (GPR75), membrane proteins. 2000+ CryoEM projects completed with resolutions reaching 1.4Å.
Cryo-ET Tomography (TOMO)
Cryo-electron tomography (CryoTEM / TOMO) for in-situ structural biology, enabling visualization of macromolecular complexes in their native cellular environment.
Data Collection
High-throughput cryo-EM data collection services on 300kV and 120kV instruments with automated processing pipelines.
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